Affordable Indian CGM Device.
Flora Life Science + Flora Genetics Vision
1. How CGM Technology Works
A CGM measures glucose continuously using a sensor under the skin that tracks glucose in interstitial fluid (not directly blood).
Core Working Principle:
Uses enzyme-based electrochemical reaction
Glucose reacts with glucose oxidase
Generates electrical current proportional to glucose level
2. Basic Architecture of a CGM Device
3 Main Components:
1. Sensor (Disposable)
Micro-needle / filament under skin
Measures glucose chemically
2. Transmitter (Reusable)
Reads sensor signal
Sends via Bluetooth
3. Receiver / Mobile App
Displays real-time data
AI analytics & alerts
👉 Modern CGMs give 288+ readings per day (every 5 min)
3. R&D Strategy to Develop Your Own CGM
Phase 1: Prototype (Low-Cost Research Model)
Start simple:
Hardware:
Electrochemical glucose sensor (lab-grade or OEM)
Microcontroller:
ESP32 (cheap + WiFi + BLE)
Analog Front End (AFE):
Convert nanoamp current → voltage
Battery + PCB
👉 CGM sensors produce very low current signals (nanoamps) → need precision electronics (AFE + amplifier).
Phase 2: Sensor Development (Most Critical & Expensive)
This is the heart of the business.
Focus on:
Enzyme immobilization (glucose oxidase)
Biocompatible coating
Flexible needle design
Modern sensors use:
Screen-printed electrodes (low-cost mass production)
Phase 3: Software & AI Layer
This is where you can win against competitors 💡
Build:
Calibration algorithm (convert current → mg/dL)
Filtering:
Moving average / Kalman filter
Predictive alerts:
Hypoglycemia warning
Mobile App:
Android-first (India market)
Phase 4: Clinical Accuracy
You must reach:
MARD (accuracy): <10–12% (industry standard)
Requires:
Human trials
Comparison with lab glucose meter
Phase 5: Regulatory Approval
In India:
CDSCO (Medical Device Approval)
ISO standards (ISO 15197, ISO 13485)
4. Why CGM is Expensive (and How You Beat It)
Current Problems:
-Imported sensors
-High R&D cost
-Disposable sensors (every 7–14 days)
-Regulatory burden
Add a title
You can use this element to explain to visitors what you do or inform them about other subjects. For instance, what is your passion and why or what does your company offer, i.e. products and services. You can hide this element in the menu on the right